• 학과 및 과정
  • 보건학과
  • 보건학전공
  • 보건정책관리학전공
  • 환경보건학과
  • 교수진
  • 겸임교수진
  • 전공의 수련과정
  • 고위정책과정

 환경보건학과

김성균
부교수: 인체노출평가 및 독성연구

• 학력

서강대학교 생명과학과, 이학사, 1994
서울대학교 보건대학원, 환경보건학, 석사, 1997
Univ. of North Carolina at Chapel Hill, 환경과학, 박사, 2006

• 연구분야

환경유해물질의 인체노출과 건강영향 및 독성 연구.
바이오마커 개발 및 분석, PBPK를 이용한 위해성평가

• 연구실적

Lee S, Kim S, Lee HK, Lee IS, Park J, Kim HJ, Lee JJ, Choi G, Choi S,
Kim S, Kim SY, Choi K, Kim S, Moon HB. (2013) Contamination of
polychlorinated biphenyls and organochlorine pesticides in breast milk
in Korea: Time-course variation, influencing factors, and exposure
assessment. Chemosphere. 93(8):1578-85.

Lee S, Kim S, Kim E, Lee IS, Choi G, Kim HJ, Park J, Lee JJ, Choi S,
Kim SY, Kim S, Kim S, Choi K, Moon HB. (2013) Polybrominated diphenyl
ethers (PBDEs) in breast milk of Korea in 2011: Current contamination,
time course variation, influencing factors and health risks. Environ Res.
126:76-83.

Jeong Y, Lee S, Kim S, Choi SD, Park J, Kim HJ, Lee JJ, Choi G, Choi S, Kim S, Kim SY, Kim YD, Cho G, Suh E, Kim SK, Eun SH, Eom S, Kim S, Kim GH, Choi K, Kim S, Moon HB. (2013) Occurrence and exposure assessment of polychlorinated biphenyls and organochlorine pesticides from homemade baby food in Korea. Sci Total Environ. S0048-9697(13)00852-8.

Kim S, Park J, Kim HJ, Lee JJ, Choi G, Choi S, Kim S, Kim SY, Moon HB, Kim S, Choi K. (2013) Association between several persistent organic pollutants and thyroid hormone levels in serum among the pregnant women of Korea. Environ Int. 59:442-8.

Kang S, Kim S, Park J, Kim HJ, Lee J, Choi G, Choi S, Kim S, Kim SY, Moon HB, Kim S, Kho YL, Choi K. (2013) Urinary paraben concentrations among pregnant women and their matching newborn infants of Korea, and the association with oxidative stress biomarkers. Sci Total Environ. 461-462:214-21.

Ji K, Kang S, Lee G, Lee S, Jo A, Kwak K, Kim D, Kho D, Lee S, Kim S, Kim S, Hiuang YF, Wu KY, Choi K. (2013) Urinary levels of N-acetyl-S-(2-carbamoylethyl)-cysteine (AAMA), an acrylamide metabolite, in Korean children and their association with food consumption. Sci Total Environ. 456-457:17-23.

Rappaport SM, Johnson BA, Bois FY, Kupper LL, Kim S, Thomas R. (2013) Ignoring and adding errors do not improve the science. Carcinogenesis. 34(7):1689-91.

Rappaport SM, Kim S, Thomas R, Johnson BA, Bois FY, Kupper LL. (2013) Low-dose metabolism of benzene in humans: science and obfuscation. Carcinogenesis 34(1):2-9.

Ji K, Kim S, Kho Y, Paek D, Sakong J, Ha J, Kim S, Choi K. (2012) Serum concentrations of major perfluorinated compounds among the general population in Korea: dietary sources and potential impact on thyroid hormones. Environ Int. 45:78-85.

Yoon HS, Lee KM, Lee KH, Kim S, Choi K, Kang D. (2012) Polycyclic aromatic hydrocarbon (1-OHPG and 2-naphthol) and oxidative stress (malondialdehyde) biomarkers in urine among Korean adults and children. Int J Hyg Environ Health. 215(4):458-64.

Kim S, Choi K, Ji K, Seo J, Kho Y, Park J, Kim S, Park S, Hwang I, Jeon J, Yang H, Giesy JP. (2011). Trans-placental transfer of thirteen perfluorinated compounds and relations with fetal thyroid hormones. Environ Sci Technol. 45(17):7465-72.

Bradford BU, Lock EF, Kosyk O, Kim S, Uehara T, Harbourt D, Desimone M, Threadgill DW, Tryndyak V, Pogribny IP, Bleyle L, Koop DR, Rusyn I. (2011). Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice. Toxicological Sciences. 120(1):206-17.

Zhang L, Tang X, Rothman N, Vermeulen R, Ji Z, Shen M, Qiu C, Guo W, Liu S, Reiss B, Freeman LB, Ge Y, Hubbard AE, Hua M, Blair A, Galvan N, Ruan X, Alter BP, Xin KX, Li S, Moore LE, Kim S, Xie Y, Hayes RB, Azuma M, Hauptmann M, Xiong J, Stewart P, Li L, Rappaport SM, Huang H, Fraumeni JF Jr, Smith MT, Lan Q. (2010). Occupational exposure to formaldehyde, hematotoxicity, and leukemia-specific chromosome changes in cultured myeloid progenitor cells. Cancer Epidemiol Biomarkers Prev. 19(1):80-8.

Rappaport SM, Kim S, Lan Q, Li G, Vermeulen R, Waidyanatha S, Zhang L, Yin S, Smith MT, Rothman N. (2010). Human benzene metabolism following occupational and environmental exposures. Chem Biol Interact. 19;184(1-2):189-95.

Rappaport, S. M., Kim, S., Lan, Q., Vermeulen, R., Waidyanatha, S., Zhang, L. P., Li, G. L., Yin, S. N., Hayes, R. B., Rothman, N., and Smith, M. T. Evidence that humans metabolize benzene via two pathways. Environmental Health Perspectives, 117: 946-952, 2009.

Kim, S., Kim, D., Pollack, G. M., Collins, L. B., and Rusyn, I. Pharmacokinetic analysis of trichloroethylene metabolism in male B6C3F1 mice: Formation and disposition of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine. Toxicol Appl Pharmacol, 238: 90-9, 2009.

Kim, S., Collins, L. B., Boysen, G., Swenberg, J. A., Gold, A., Ball, L. M., Bradford, B. U., and Rusyn, I. Liquid chromatography electrospray ionization tandem mass spectrometry analysis method for simultaneous detection of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine. Toxicology, 2009.

Taylor, D. J., Kupper, L. L., Johnson, B. A., Kim, S., and Rappaport, S. M. Statistical Models for Exposure-Biomarker Relationships With Measurement Error and Censoring. Journal of Agricultural Biological and Environmental Statistics, 13: 367-387, 2008.

Lin, Y. S., Vermeulen, R., Tsai, C. H., Waidyanatha, S., Lan, Q., Rothman, N., Smith, M. T., Zhang, L. P., Shen, M., Li, G. L., Yin, S., Kim, S., and Rappaport, S. M. Albumin adducts of electrophilic benzene metabolites in benzene-exposed and control workers. Environmental Health Perspectives, 115: 28-34, 2007.

Kim, S., Lan, O., Waidyanatha, S., Chanock, S., Johnson, B. A., Vermeulen, R., Smith, M. T., Zhang, L. P., Li, G. L., Shen, M., Yin, S. N., Rothman, N., and Rappaport, S. M. Genetic polymorphisms and benzene metabolism in humans exposed to a wide Range of air concentrations. Pharmacogenetics and Genomics, 17: 789-801, 2007.

Vermeulen, R., Lan, Q., Li, G. L., Rappaport, S. M., Kim, S., de Joode, B. V., Shen, M., Xu, B. H., Smith, M. T., Zhang, L. P., Yin, S. N., and Rothman, N. Assessment of dermal exposure to benzene and toluene in shoe manufacturing by activated carbon cloth patches. Journal of Environmental Monitoring, 8: 1143-1148, 2006.

Lan, Q., Vermeulen, R., Zhang, L. P., Li, G. L., Rosenberg, P. S., Alter, B. P., Shen, M., Rappaport, S. M., Weinberg, R. S., Chanock, S., Waidyanatha, S., Rabkin, C., Hayes, R. B., Linet, M., Kim, S., Yin, S., Rothman, N., and Smith, M. T. Benzene exposure and hematotoxicity - Response. Science, 312: 998-999, 2006.

Lan, Q., Vermeulen, R., Zhang, L. P., Li, G. L., Rosenberg, P. S., Alter, B. P., Shen, M., Rappaport, S. M., Weinberg, R. S., Chanock, S., Waidyanatha, S., Rabkin, C., Hayes, R. B., Linet, M., Kim, S., Yin, S., Rothman, N., and Smith, M. T. Benzene exposure and hematotoxicity - Response (vol 312, pg 998, 2006). Science, 313: 442-442, 2006.

Kim, S., Vermeulen, R., Waidyanatha, S., Johnson, B. A., Lan, Q., Smith, M. T., Zhang, L. P., Li, G. L., Shen, M., Yin, S. N., Rothman, N., and Rappaport, S. M. Modeling human metabolism of benzene following occupational and environmental exposures. Cancer Epidemiology Biomarkers & Prevention, 15: 2246-2252, 2006.

Kim, S., Vermeulen, R., Waidyanatha, S., Johnson, B. A., Lan, Q., Rothman, N., Smith, M. T., Zhang, L. P., Li, G. L., Shen, M., Yin, S. N., and Rappaport, S. M. Using urinary biomarkers to elucidate dose-related patterns of human benzene metabolism. Carcinogenesis, 27: 772-781, 2006.

Lan, Q., Zhang, L. P., Shen, M., Smith, M. T., Li, G. L., Vermeulen, R., Rappaport, S. M., Forrest, M. S., Hayes, R. B., Linet, M., Dosemeci, M., Alter, B. P., Weinberg, R. S., Yin, S. N., Yeager, M., Welch, R., Waidyanatha, S., Kim, S., Chanock, S., and Rothman, N. Polymorphisms in cytokine and cellular adhesion molecule genes and susceptibility to hematotoxicity among workers exposed to benzene. Cancer Research, 65: 9574-9581, 2005.

Lan, Q., Zhang, L. P., Li, G. L., Vermeulen, R., Weinberg, R. S., Dosemeci, M., Rappaport, S. M., Shen, M., Alter, B. P., Wu, Y. J., Kopp, W., Waidyanatha, S., Rabkin, C., Guo, W. H., Chanock, S., Hayes, R. B., Linet, M., Kim, S., Yin, S. N., Rothman, N., and Smith, M. T. Hematotoxicity in workers exposed to low levels of benzene. Science, 306: 1774-1776, 2004.

Lee, J., Kang, D., Lee, K. H., Ichiba, M., Zhang, J., Tomokuni, K., Hwang, E. S., Park, C. G., Ha, M., Kim, S., Han, S. B., Choi, J. W., Lee, E., Jang, J. Y., Strickland, P. T., Hirvonen, A., and Cho, S. H. Influence of GSTM1 genotype on association between aromatic DNA adducts and urinary PAH metabolites in incineration workers. Mutat Res, 514: 213-21, 2002.

Han, J. H., and Kim, S. K. Urinary cotinine concentrations in active and passive smokers. J. Environmental Mutagens and Carcinogens, 21: 32-39, 2000.
Kim, S. K., Choi, K. H., and Zong, M. S. A study on the effect of the biodegradability of the composting bulking agent n the sine manure-composting. Kor. J. Env. Hlth. Soc., 23: 35-43, 1997.

Zong, M. S., Park, S. H., Choi, K. H., Son, H. S., Kim, S. K., and Park, J. Y. A study on optimum mixing ratio of paper wastes bulking agent in composting of swine feces. Kor. J. Env. Hlth. Soc., 22: 82-90, 1996.

• 이전 연구업적리스트



위치: 220동 731호
전화: 880- 2732
Email: ddram2@snu.ac.kr

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