| GSPH 동정 | 교수진 동정

원성호 교수 | 보건통계학연구실(II)

▷진행 중 연구과제

1. 복합 질환 예측 모형 개발 알고리즘 개발 및 한국인 유전체정보 컨텐츠 확립

2. 차세대 유전체 자료를 활용한 통합 유전 연관 분석도구의 개발

3. 차세대 생명정도 활용을 위한 다양성 소프트웨어 개발

4. 약물유전체 지식기반 멀티오믹스 자료의 고급 통계분석 플랫폼 구축

▷ Publication list

Park S, Lee S, Lee Y, Lange C, Won S†. Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families. BMC Medical Genetics (SCIE) 2015 Aug;16:62.

Kim SH, Huh K, Won S, Lee KW, Park MJ†. A Significant Increase in the Incidence of Central Precocious Puberty among Korean Girls from 2004 to 2010. PLoS One (SCIE) 2015 Nov 5;10(11):e0141844

Hardin M†, Cho MH, McDonald ML, Wan E, Lomas DA, Coxson HO, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, Rennard S, Wouters E, Bakke P, Bhatt SP, Kim V, Ramsdell J, Regan EA, Make BJ, Hokanson JE, Crapo JD, Beaty TH, Hersh CP; ECLIPSE and COPDGene Investigators; COPDGene Investigators—clinical centers; COPDGene Investigators-clinical centers. A genome-wide analysis of the response to inhaled β2-agonists in chronic obstructive pulmonary disease. Pharmacogenomics Journal (SCIE) 2015 Oct 27

Hayden LP†, Hobbs BD, Cohen RT, Wise RA, Checkley W, Crapo JD, Hersh CP; COPDGene Investigators. Childhood pneumonia increases risk for chronic obstructive pulmonary disease: the COPDGene study. Respiratory Research (SCIE) 2015 Sep 21;16(1):115.

Regan EA†, Lynch DA, Curran-Everett D, Curtis JL, Austin JH, Grenier PA, Kauczor HU, Bailey WC, DeMeo DL, Casaburi RH, Friedman P, Van Beek EJ, Hokanson JE, Bowler RP, Beaty TH, Washko GR, Han MK, Kim V, Kim SS, Yagihashi K, Washington L, McEvoy CE, Tanner C, Mannino DM, Make BJ, Silverman EK, Crapo JD; Genetic Epidemiology of COPD (COPDGene) Investigators. Clinical and Radiologic Disease in Smokers With Normal Spirometry. JAMA Internal Medicine (SCI) 2015 Sep;175(9):1539-49.

Cho Y, Shin SY, Won S, Relton CL, Davey Smith G, Shin MJ†. Alcohol intake and cardiovascular risk factors: A Mendelian randomisation study. Scientific Reports (SCI) 2015 Dec 21;5:18422.

Kim YJ, Lee J, Kim BJ, T2D-Genes Consortium, Park T. A new strategy for enhancing imputation quality of rare variants from next-generation sequencing data via combining SNP and exome chip data. BMC Genomics (SCIE). 2015 Dec 29;16(1)